游晶教授 / 主任医师医院：昆明医科大学第一附属医院科室：肝病专科专家门诊

暂无就医经验

擅长：

各种病毒性肝炎及肝病的临床诊断治疗和科学研究

简介：

游晶，女，泰国宋卡王子大学医学博士，教授，主任医师，硕士生导师，云南省中青年学术和技术带头人，昆明医学院骨干教师，师从于国际著名医学家Virasakdi C.教... 更多简介：游晶，女，泰国宋卡王子大学医学博士，教授，主任医师，硕士生导师，云南省中青年学术和技术带头人，昆明医学院骨干教师，师从于国际著名医学家Virasakdi C.教授、Hutcha S.教授及Alan G.教授。自1984年工作后一直从事内科学、感染病学的临床、科研和教学工作。多次被评为职业道德先进个人、先进工作者、优秀医师、优秀教师等。主持/参加完成国际科研基金项目、省级科研基金项目、卫生部国际合作项目等10多项。在国内外核心期刊发表学术论文60余篇，被美国科学引文索引（SCI）收录12篇。获科技成果奖多项。参加国际学术会议进行学术交流20多次。国内外多家杂志（Hepatology International European Journal of Gastroenterology and Hepatology World Journal of Gastroenterology Journal of Medical Virology Clinical Epidemiology Clinical Hepatology Philippine Journal Science Current Topic in Virology Journal of Clinical Hepatology World Journal of Infection et al）编委及审稿专家。擅长各种病毒性肝炎及肝病的临床诊断治疗和科学研究。近五年来在国内外核心期刊发表的主要论著： [1]Jing You Lin Zhuang Yi-Feng Zhang Hong-Ying Chen Hutcha Sriplung Alan Geater Virasakdi Chongsuvivatwong Teerha Piratvisuth Edward McNeil Lan Yu Bao-Zhang Tang Jun-Hua Huang. Peripheral T-lymphocyte subpopulations in different clinical stages of chronic HBV infection correlate with HBV load. World J Gastroenterol 2009;15(27):3382-3393 （SCI 收录） [2]Jing You Hutcha Sriplung Alan Geater Virasakdi Chongsuvivatwong Lin Zhuang Yun-Li Li Hua Lei Jun Liu Hong-Ying Chen Bao-Zhang Tang Jun-Hua Huang. Impact of viral replication inhibition by entecavir on peripheral T lymphocyte subpopulations in chronic hepatitis B patients. BMC Intectious Diseases 2008 8:123 （SCI 收录） [3]Jing You Hutcha Sriplung Virasakdi Chongsuvivatwong Alan Geater Lin Zhuang Jun-Hua Huang Hong-Ying Chen Lan Yu Bao-Zhang Tang. Profile spectrum and significance of hepatitis B virus genotypes in chronic HBV-infected patients in Yunnan China. Hepatobiliary Pancreat Dis Int 2008;7(3):271-279 （SCI 收录） [4]Jing You Hutcha Sriplung Alan Geater Virasakdi Chongsuvivatwong Lin Zhuang Hong-Ying Chen Lang Yu Bao-Zhang Tang Jun-Hua Huang. Effect of viral load on T-lymphocyte failure in patients with chronic hepatitis B. World J Gastroenterol 2008 14(7):1112-1119 （SCI 收录） [5]Jing You Hutcha Sriplung Alan Geater Virasakdi Chongsuvivatwong Lin Zhuang Hong-Ying Chen Jun-Hua Huang Bao-Zhang Tang. HBV DNA is more powerful than HBeAg in predicting peripheral T-lymphocyte subpopulation in chronic HBV-infected individuals with normal liver function tests. World J Gastroenterol 2008 14(23):3710-3718 （SCI 收录） [6]Jing You Lin Zhuang Hong-Ying Cheng Shou-Ming Yan Lan Yu Jun-Hua Huang Bao-Zhang Tang Meng-Ling Huang Yong-Liang Ma Virasakdi Chongsuvivatwong Hutcha Sriplung Alan Geater Yan-Wei Qiao Rong-Xue Wu. Efficacy of Thymosin alpha-1 and Interferon alpha in the Treatment of Chronic Viral Hepatitis B: A Randomized Controlled Study. World J Gastroenterol 2006 12(41):6715-6721 （SCI 收录） [7]Yanhua Che Sawitri Assanangkornchai Edward McNeil Virasakdi Chongsuvivatwong Jianhua Li Alan Geater Jing You. Predictors of early dropout in methadone maintenance treatment program in Yunnan province China. Drug Alcohol Rew 2010;29(3):263-7 （SCI 收录） [8]Yanhua Che Sawitri Assanangkornchai Edward McNeil Jianhua Li Jing You Virasakdi Chongsuvivatwong. Patterns of attendance in methadone maintenance treatment program in Yunnan Province China. Am J Drug Alcohol Abuse 2011;37(3):148-54 （SCI 收录） [9]Bao Zhang Tang Jing You Hong Ying Chen Lu Zhang Gao Chen. Therapeutic effect of Lamivudine on subacute hepatic failure with hepatitis B virus infection. Current Topics in Virology 2007; 6:41-45 [10]Jing You Li-Fan Yuan Yi-Feng Zhang Hai-Qiu Yang Lin Zhuang Hong-Ying Chen Jun-Hua Huang Bao-Zhang Tang Hui Wang. The relationship of peripheral T cell subsets and serum transforming growth factor β1 level in patients with chronic hepatitis B virus infection. Hepatol Int 2009 3:35 [11]Jing You Lin Zhuang Hutcha Sriplung Alan Geater Virasakdi Chongsuvivatwong Yun-Li Li Hua Lei Jun Liu Hong-Ying Chen Bao-Zhang Tang Jun-Hua Huang. Entecavir therapy for up to 48 weeks in Chinese patients with HBeAg-positive chronic hepatitis B. Hepatol Int 2009 3:119 [12]Lin Zhuang Jing You Yi-Feng Zhang Yun-Li Li Hua Lei Rui-Dong Yang Hong-Ying Chen Jun-Hua Huang Bao-Zhang Tang. Adefovir dipivoxil for treatment of lamivudine-resistant hepatitis B e antigen- positive chronic hepatitis B. Hepatol Int 2009 3:133 [13]Jing You Xu Zhang Lin Zhuang Hong-Ying Chen Bao-Zhang Tang Qing-Qing Wang Li Chen. The relationship between HBV precore region mutation and the variation of T-lymphocyte subpopulations in patients with chronic hepatitis B. Int J Infect Dis 2009 13(Suppl 1):S72 [14]Lin Zhuang Jing You Hong-Ying Chen Bao-Zhang Tang Meng-Ling Huang Yong-Liang Ma Jun-Hua Huang Rong-Xue Wu. Thymosin alpha-1 therapy in Chinese patients with chronic hepatitis B: results from a randomized controlled clinical trial. Int J Infect Dis 2009 13(Suppl 1):S80 [15]Jing You Fang-Rong Zhang Xu Zhang Hui Wang Li-Fang Yuan Hong-Ying Chen Qion-Fen Li Guo-Yan Bai Lin Zhuang Bao-Zhang Tang Jun-Hua Huang. The variation of serum level of interleukin-15 and it’s significances in patients with chronic hepatitis B virus infection. Hepatol Int 2010 4:103 [16]Jing You Hui Wang Hong-Ying Chen Yi-Hui Chen Zhi-Wen Duan Xing-Xing Shi Li-Wen Yang Yan-Ping Liang Lin Zhuang Bao-Zhang Tang Jun-Hua Huang. The variation of peripheral T-lymphocyte subpopulations and serum Interferon-γ and Interleukin-4 level in patients with chronic hepatitis B virus infection. Hepatol Int 2010 4:112 [17]Jing You Lin Zhuang Hong-Ying Chen Jun-Hua Huang Bao-Zhang Tang Meng-Lin Huang. Variation in liver histopathology in chronic HBV-infected individuals with normal liver function tests correlates with HBV replication. Hepatol Int 2010 4:16 [18]Lin Zhuang Jing You Lei Kong Hua Lei Rui-Dong Yang Xu Zhang Qing-Qing Wang. Efficacy of 96 weeks adefovir dipivoxil treatment in HBeAg positive chronic hepatitis B patients with various baseline biochemical levels. Hepatol Int 2010 4:19 [19]Jing You Qing-Qing Wang Lin Zhuang Xia Feng Rui-Dong Yang Rong Liu Hong-Ying Chen Hui-Juan Yang Qiang-Ming Sun Yong-Sheng Zhang Qiong-Feng Li Li Chen Hai-Qiu Yang Yi-Feng Zhang Hong Dai Zhi-Wen Duan. The role of Interleukin-12p70 in dengue virus infection. Int J Infect Dis 2010 14S2:S14 [20]Lin Zhuang Jing You Lei Kong Hua Lei Hong-Ying Chen Qing-Qing Wang. Prevalence of Transfusion transmitted virus in patients with viral liver disease. Int J Infect Dis 2010 14S2:S57 [21]Jing You Xia Feng Rui-Dong Yang Rong Liu Qing-Qing Wang Hong-Ying Chen Hui-Juan Yang Qiang-Ming Sun Yong-Sheng Zhang Qiong-Feng Li Li Chen Hai-Qiu Yang Yi-Feng Zhang Hong Dai Zhi-Wen Duan. A shift from a Th1 to a Th2 immune response in patients with dengue virus infection. Int J Infect Dis 2010 14S2:S94 [22]Jing You Lin Zhuang Hong-Ying Chen Xia Feng Yan-Hua Che Ying-Li Cun Yi-Feng Zhang Yon-Sheng Zhang Bao-Zhang Tang Meng-Ling Huang Yong-Liang Ma Jun-Hua Huang Shao-Ming Yan Qing-Qing Wang Li Chen Chao Chen Jun-Min Li. Interferon therapy decreased the incidence of hepatocellular carcinoma in patients with chronic hepatitis B: a prospective cohort study. Hepatol Int 2011 5:102 [23]Lin Zhuang Jing You Shao-Ming Yan Jun-Hua Huang Lei Kong Hua Lei Yan-Li Ma Yun-Li Li Hong-Ying Chen Bao-Zhang Tang Qing-Qing Wang Xu Zhang Li Chen Jun-Ming Li Chao Chen. Long-term therapy with adefovir dipivoxil for lamivudine-resistant HBeAg positive chronic hepatitis B: results from 104 weeks antiviral treatment. Hepatol Int 2011 5:109 [24]Jing You Lin Zhuang Hong-Ying Chen Xia Feng Lei Kong Hua Lei Yan-Li Ma Yun-Li Li Wei-Bo Yang Jun-Hua Huang Shao-Ming Yan Yan-Hua Che Qing-Qing Wang Li Chen. Long-term therapy with adefovir dipivoxil for HBeAg positive chronic hepatitis B: results from 144 weeks adefovir dipivoxil treatment. Int J Infect Dis 2011 15S2:S30 [25]Jing You Lin Zhuang Jun-Hua Huang Yan-Hua Che Shao-Ming Yan Hua Lei Lei Kong Yun-Li Li Hong-Ying Chen Bao-Zhang Tang Qing-Qing Wang Yan-Li Ma Li Chen Hai-Bing Wang. Severity of hepatic inflammation and fibrosis in patients with chronic HBV infection with normal liver function test correlated with viral load and HBeAg status. Int J Infect Dis 2011 15S2:S69 [26]Lin Zhuan Jing You Shao-Ming Yan Jun-Hua Huang Lei Kong Hua Lei Yan-Li Ma Yun-Li Li Hong-Ying Chen Bao-Zhang Tang Qing-Qing Wang Xu Zhang Li Chen Hai-Bing Wang Jun-Ming Li Chao Chen. HBV and HCV infection play an important role in the progression to liver cirrhosis and hepatocellular carcinoma in alcoholics. Int J Infect Dis 2011 15S2:S69 [27]游晶庄林马永良唐宝璋. 慢性乙型肝炎的Th细胞亚群和细胞因子网络失衡. 世界华人消化杂志 2007;15(8):791-799 [28]游晶袁丽芳陈红英唐宝璋王辉. TGF-β1与慢性乙型肝炎的关系. 世界华人消化杂志 2007;15(8):869-872 [29]游晶庄林陈红英杨海秋唐宝璋黄梦玲. 乙型肝炎病毒基因型及其临床意义的研究进展. 世界华人消化杂志 2007;15(9):921-928 [30]王辉游晶袁丽芳陈红英唐宝璋. 辅助性T细胞的研究概况及进展. 世界华人消化杂志 2007;15(13):1532-1536 [31]游晶庄林陈红英台虹宋建新欧阳红梅唐宝璋 Hutcha Sriplung Virasakdi Chongsuvivatwong Alan Geater 张一凤杨海秋黄俊华. 国人慢性HBV携带者HBV复制水平与T细胞亚群变化的关系. 世界华人消化杂志 2007;15(35):3722-3727 [32]庄林游晶陈红英俞岚孔雷唐宝章黄俊华袁绍明 Hutcha Sriplung Virasakdi Chongsuvivatwong Alan Geater 袁丽芳王辉. 云南地区乙型肝炎病毒基因型分布与临床的相关性. 世界华人消化杂志 2007;15(19):2120-2127 [33]游晶庄林李云丽陈红英俞岚唐宝章黄梦玲黄俊华袁绍明王辉袁丽芳. 云南汉族慢性乙型肝炎患者HBV基因型及其临床意义. 中华微生物学和免疫学杂志 2007;27(6):564 [34]陈超游晶杨微波张宏丽李俊敏戴虹张禄 . HIV-1 Nef 作用机制的研究进展. 重庆医学 2012;41(6) [35]黄俊华游晶. ALT正常的HBV慢性携带者肝组织病理结果分析. 临床肝胆病杂志 2007;23(1):6-8 [36]庄林游晶雷华李云丽孔蕾王晴晴胡明芬柏宝. ALT轻度升高HBV DNA水平不同的慢性乙型肝炎患者肝组织学差异探讨. 临床肝胆病杂志 2011;27(12):1278-1281 1284 近五年来对外学术交流： 1．The 18th Wonca World Conference (Wonca 2007) . July 24-27 2007 The Suntec Singapore Convention and Exhibition Centre Singapore. 2．The 4th Hong Kong-Shanghai International Liver Congress (ILC 2008) “Molecular Targeting in Liver Disease–From Bench to Besides” 12-15 June 2008 Hong Kong Convention & Exhibition Centre Hong Kong China. 3．19th Conference of the APASL 2009 Hong Kong (APASL Hong Kong 2009) 13-16 February 2009 Hong Kong 4．3rd Ditan International Conference on Infectious Diseases (3rd DICID 2009) 30 July- 2 Ausust 2009 Beijing 5．14th International Congress on Infectious Diseases (ICID) 2010 Miami Florida USA 9-12 March 2010 Miami Florida USA. 6．20th Conference of the APASL 2010 Beijing 25-28 March 2010 China National Convention Centre Beijing China. 7．4th Ditan International Conference on Infectious Diseases (DICID) 15-18 July 2010 Beijing International Convention Centre China 8．The 61st Annual Meeting of The American Association for the Study of Liver Diseases (AASLD) 29 October- 2 November 2010 Boston Hynes Convention Center USA. 9．The 21th Conference of the APASL 2011 Bangkok 17-20 February 2011 Bangkok Thailand. 10．5th Ditan International Conference on Infectious Diseases (DICID) 14-18 July 2011 Beijing International Convention Centre China 11．The 62nd Annual Meeting of The American Association for the Study of Liver Diseases (AASLD) November 4-8 2011 Moscone West Convention Center San Francisco California USA 收起

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张禄副主任医师副教授

擅长：各种病毒性肝炎防治，肝脏弹性检测
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擅长：中西医治疗肝病

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昆明医科大学第一附属医院

游晶 教授 / 主任医师 医院： 昆明医科大学第一附属医院 科室： 肝病专科专家门诊

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游晶教授 / 主任医师医院：昆明医科大学第一附属医院科室：肝病专科专家门诊

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